Peptide Database

Peptide NameRegenerating islet-derived protein 3-beta (REG-3-beta) (Pancreatitis-associated protein 1) (Peptide 23) (REG-2) (Regenerating islet-derived protein III-beta) (Reg III-beta) [Cleaved into: Regenerating islet-derived protein 3-beta 16.5 kDa form; Regenerating islet-derived protein 3-beta 15 kDa form]

Function Ontology

Antimicrobial

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC876H1329N235O253S13

DescriptionStandard

        MLHRLAFPVMSWMLLSCLMLLSQVQGEDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG
    

Molecular Weight19617.19 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0040

GRAVY Index-0.23

Hydrophobic Moment 0.63

Boman Index0.07

Instability Index42.34

Aliphatic Index 71.89

Aromaticity 0.1200

Extinction Coeff. Reduced 48930.00

Extinction Coeff. Oxidized 49305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7791.96

LogP -79.26

H-bond Donors 277.0

H-bond Acceptors 270.0

Rotatable Bonds 628.0

Heavy Atoms 1377.0

Ring Count 41.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319297 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Lectin Non-hemolytic

TargetS. enteritidis