‹ ›
MYP_118467
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Virucidal activity
Standard
20 amino acids
C98H178N28O21
Standard
Sequence
RRKKAAVALLPAVLLALLAP
Physicochemical Analysis
2084.64 Da
12.00
3.76
3.55
0.1879
1.10
0.32
0.22
67.03
176.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.48
-2.89
27.0
25.0
67.0
147.0
2.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0377160 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); MDCK
95 %
Hemagglutinin assay
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0403155 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Signal peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 1 (Virus entry); Vero
4 %
Viral titer
PaperPeptides containing membrane-transiting motifs inhibit virus entry. | Bultmann H, Brandt CR. | J Biol Chem. 2002 | PMID:12130644 PMID12130644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12130644/
RECORD: Rec_0420085 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
EB peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV Anti-Influenza Entry inhibitor Virucidal
HSV-1
15 μM
IC50
PaperThe virucidal EB peptide protects host cells from herpes simplex virus type 1 infection in the presence of serum albumin and aggregates proteins in a detergent-like manner; Patent: Method of inhibiting influenza infection with antiviral peptides PMID20643896 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20643896/ PatentUS 7432045 B2
FIRST PREV 1 2 3 4
Showing 3 records on this page · Page 4 of 4