Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC414H683N99O107S2

DescriptionStandard

        MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINTGSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW
    

Molecular Weight8823.58 Da

Isoelectric Point (pI)10.08

Net Charge (pH 7.0)6.49

Net Charge (pH 7.4) 6.26

Charge Density (pH 7.0) 0.0746

GRAVY Index1.08

Hydrophobic Moment 0.62

Boman Index0.44

Instability Index19.49

Aliphatic Index 135.75

Aromaticity 0.0805

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3222.08

LogP -22.68

H-bond Donors 113.0

H-bond Acceptors 116.0

Rotatable Bonds 291.0

Heavy Atoms 622.0

Ring Count 10.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128800 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus sp. HMSC077E04 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0143223 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal