Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Standard StatusStandard

Sequence Length1086 amino acids

Chemical FormulaC5271H8240N1514O1626S30

DescriptionStandard

        TRQCAVFQNQSVPEVVEQVLRKHGLEGADFEFRLERAYPSREIITQWQETDLQFIRRILSEVGIYWRTEMDDVRGLDTYIFADSQLHYQFDVQLPYSEPSGLFDGAAESVWDVRTWHNVATGTVTTRDYNYRTVTTPMNATVSVRNDAVTTGEHYRYAAPYREAGDDASPEPETESGAFYARLHHERELNRSARIHLFSNAAHLSPGQVLEPQGDVITDLKEGIVLTLVTYRGARDSRLHVSAWGMPYSERYCFRPAEIPRPVIPGTLPARIESRKKNDIYAHLDGQGRYRVKMDFDREETEPGFGYLWLRMAKPCAGETLGWHTPLIDGTEVAIAYSNGDIDLPYIAYALHDAEHPDPVNRDNHTRNILRTPANSKLRMEDRRGEEHIKLATEYGKTQLNSGHLVDSQGQLRGKGTELRTDEWGTLRAGKGLFVAADAQVKAQGEALDMDAALKEIDRLNQQLQQLETAAERAQALKADIDSQIQMFEQRLKPLNEAVLFSAPEGIALTSGEDMQLAAGQNLAVNAGGDIGSGTMGNLTALAGERLGLFARSGQLSVKSGEGAVDVQAQNGSMRLFAEKKLTISSESDISFTGKKRITLIGGGSYLRLEAGKVEYGTTAKYLRKVKRTMAASASSEAAQTVSLPTPVTMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAKEPVEHFGQMTIFARPVEDDCCGYGRQHEHTDDEVIQHAQSARKRKPDVGGAKAPAPAGATAAPLALGTATGVMTQVWGEWSLTGVLGAARGIPYIGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSQNNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSGIKLPDQATILVTPIPDGKDEYTTSPFPVPEERDFNDYILVFPAGSGIKPIYVYLKTARDEPGVATGKGKILSGSEKWLEAASSGLGAPVPSQIADKLRGQEFSNFDAFRAAFWKAVAADPELSLQFKSSNLDRMRIGKAPRCVRVEHVGKRKSFELHHVDNISDGGAVMDCDNVRVTTPKRHIDIHKGS
    

Molecular Weight119796.93 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-18.04

Net Charge (pH 7.4) -20.08

Charge Density (pH 7.0) -0.0166

GRAVY Index-0.51

Hydrophobic Moment 0.80

Boman Index-0.05

Instability Index32.98

Aliphatic Index 73.35

Aromaticity 0.0801

Extinction Coeff. Reduced 147140.00

Extinction Coeff. Oxidized 147640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306158 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase

TargetEscherichia coli