Peptide Database

Peptide NameBeta-defensin 14 [C11,18,23,33,40,41A], Defb14 [C11,18,23,33,40,41A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC221H380N76O56

DescriptionStandard

        FLPKTLRKFFARIRGGRAAVLNALGKEEQIGRASNSGRKAARKKK
    

Molecular Weight4997.86 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)11.76

Net Charge (pH 7.4) 11.54

Charge Density (pH 7.0) 0.2613

GRAVY Index-0.73

Hydrophobic Moment 0.78

Boman Index-0.31

Instability Index28.83

Aliphatic Index 74.00

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2214.93

LogP -23.95

H-bond Donors 81.0

H-bond Acceptors 68.0

Rotatable Bonds 179.0

Heavy Atoms 353.0

Ring Count 4.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083226 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa PAO1

Activity1.5 μg/mL

MethodMBC

RECORD: Rec_0393299 VERIFIED: YES