Peptide Database

Peptide NameBovine tracheal antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC169H302N58O45S7

DescriptionStandard

        NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
    

Molecular Weight4091.02 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.40

Charge Density (pH 7.0) 0.2288

GRAVY Index-0.09

Hydrophobic Moment 0.69

Boman Index-0.15

Instability Index32.82

Aliphatic Index 71.58

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1681.31

LogP -20.77

H-bond Donors 65.0

H-bond Acceptors 61.0

Rotatable Bonds 138.0

Heavy Atoms 279.0

Ring Count 3.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067846 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae 13883

Activity12-25 μg/mL

MethodMIC

RECORD: Rec_0070197 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide5-34, 12-27, 17-35

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetE. coli, S. aureus, P. aeruginosa, C. albicans

RECORD: Rec_0082779 VERIFIED: NO

Provenance & Taxonomy

OrganismBovine chromaffin [Animal]; Bos taurus [Animal]

Tax ID33208; 9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0168267 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida ablicans

Activity6-12 μg/mL

MethodMIC

RECORD: Rec_0177223 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli D31

Activity12-25 μg/mL

MethodMIC

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