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MYP_118367
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Basic Information
Mastoparan M
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKAIAALAKKLL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
-2.84
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007768 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 15935330 | PubMed PMID: 27591703 PMID15935330;27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15935330/
RECORD: Rec_0008345 VERIFIED: YES
Provenance & Taxonomy
Vespa mandarinia [Animal]
Mastoparan
7446
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antifungal
Candida albicans
22 μM
MIC
PaperCan BioSAXS detect ultrastructural changes of antifungal compounds in Candida albicans?-an exploratory study PMID37533629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37533629/
RECORD: Rec_0016452 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPubMed PMID: 15935330 | PubMed PMID: 27591703 PMID15935330;27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15935330/
RECORD: Rec_0025884 VERIFIED: YES
Provenance & Taxonomy
Vespa mandarinia [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
6-16
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus CCRC12652 or CCRC15211
32-64 μg/mL
MIC
PaperA new mast cell degranulating peptide, mastoparan-M, in the venom of the hornet Vespa mandarinia.
RECORD: Rec_0068742 VERIFIED: YES
Provenance & Taxonomy
Vespa mandarinia [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
32 μg/mL
MIC
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