Peptide Database

Peptide NamePeptide 18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC57H80N22O8

DescriptionStandard

        RRRRWWW
    

Molecular Weight1201.39 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.5372

GRAVY Index-2.96

Hydrophobic Moment 0.24

Boman Index-1.10

Instability Index335.89

Aliphatic Index 0.00

Aromaticity 0.4286

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 532.89

LogP -1.47

H-bond Donors 23.0

H-bond Acceptors 12.0

Rotatable Bonds 35.0

Heavy Atoms 87.0

Ring Count 6.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374247 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa

Activity80.99975111 μM

MethodMIC

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