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MYP_118355
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
10 amino acids
C49H78N14O16
Standard
Sequence
DAQSAPLRVY
Physicochemical Analysis
1119.23 Da
5.84
-0.24
-0.44
-0.0240
-0.36
0.39
-0.07
83.92
88.00
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
499.18
-5.05
17.0
16.0
33.0
79.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0220135 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0254050 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
13.0
IC50
PaperTavares T., del Mar Contreras M., Amorim M., Pintado M., Recio I., Malcata F. X.. Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: in vitro effect and stability to gastrointestinal enzymes. Peptides, 32, 1013-1019, 2011.
RECORD: Rec_0287920 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Glycosylation-associated glycomacropeptide context
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
11.62 μM
IC50
PaperThe Portuguese Paradox: Why do some inhabitants of Portugal appear to live so long when their diet is based on whey cheese? | Tavares, TG. et al. | DOI: 10.1016/j.foodchem.2011.09.052 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0408605 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
10 mmHg
SBP decrease
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0421533 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
12.2 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
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