MYP_118317
Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Standard
39 amino acids
C182H268N62O48S8
Standard
Sequence
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLPCTCYRCG
Physicochemical Analysis
4348.98 Da
8.94
4.94
4.46
0.1266
-0.65
0.60
-0.10
45.72
20.00
0.1282
9970.00
10470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1748.62
-21.80
70.0
64.0
131.0
300.0
12.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039506 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0062581 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
29158
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains 4 disulfide bonds (C4-C25, C10-C33, C14-C35, and C21-C38) among which the fourth S-S bond is not important for antibacterial activity. Trp28 is hydroxylated. This hydroxylation appears no to influence antimicrobial activity
Bio-Activity Profile
Antimicrobial
V. splendidus
1.6 μg/mL
MIC
RECORD: Rec_0136126 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
29158
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains 4 disulfide bonds (C4-C25, C10-C33, C14-C35, and C21-C38) among which the fourth S-S bond is not important for antibacterial activity. Trp28 is hydroxylated. This hydroxylation appears no to influence antimicrobial activity
Bio-Activity Profile
Antimicrobial
Micrococcus luteus
0.08 μg/mL
MIC
RECORD: Rec_0195815 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
29158
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains 4 disulfide bonds (C4-C25, C10-C33, C14-C35, and C21-C38) among which the fourth S-S bond is not important for antibacterial activity. Trp28 is hydroxylated. This hydroxylation appears no to influence antimicrobial activity
Bio-Activity Profile
Antimicrobial
Escherichia coli
6.4 μg/mL
MIC
RECORD: Rec_0218012 VERIFIED: NO
Provenance & Taxonomy
Mediterranean mussel [Animal]; Animalia [Animal]
Defensin
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-21; 10-25; 14-33
Bio-Activity Profile
Antimicrobial
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