Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC426H675N121O128S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFAEVQELEEAGSNDTPGAAYQEMSMESRMMPDHTRQKRQSHLSLCRWCCNCCRANKGCGFCCKF
    

Molecular Weight9988.56 Da

Isoelectric Point (pI)6.69

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0044

GRAVY Index0.04

Hydrophobic Moment 0.66

Boman Index0.04

Instability Index57.50

Aliphatic Index 66.22

Aromaticity 0.0778

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3993.67

LogP -42.96

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 331.0

Heavy Atoms 689.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412934 VERIFIED: NO

Provenance & Taxonomy

OrganismSander lucioperca [Animal]

FamilyHepcidin

Tax ID283035

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal