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MYP_118244
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Basic Information
Mastoparan B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C78H137N19O17
Standard
Sequence
LKLKSIVSWAKKVL
Physicochemical Analysis
1613.04 Da
10.48
3.76
3.55
0.2683
0.57
0.66
0.13
-31.77
160.00
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.95
-1.56
22.0
21.0
57.0
114.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095302 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Hypotensive
Guinea-pig erythrocytes
15 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11478963/ PMID11478963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11478963/
RECORD: Rec_0101742 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2019/0276505 A1 Evidence URLhttps://patents.google.com/patent/US20190276505A1/en PatentUS 2019/0276505 A1
RECORD: Rec_0104790 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Pseudomonas aeruginosa
128 μg/mL
MIC
PaperInteraction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity
RECORD: Rec_0106395 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. tropicalis CT 1003
1.24 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0122915 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. tropicalis CT 1006
1.24 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
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