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MYP_118244
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Basic Information
Mastoparan B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C78H137N19O17
Standard
Sequence
LKLKSIVSWAKKVL
Physicochemical Analysis
1613.04 Da
10.48
3.76
3.55
0.2683
0.57
0.66
0.13
-31.77
160.00
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.95
-1.56
22.0
21.0
57.0
114.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066197 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. tropicalis CT 1005
0.62 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0078369 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Hypotensive
Guinea-pig erythrocytes
20 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11478963/ PMID11478963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11478963/
RECORD: Rec_0080977 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
2.52 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0086503 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anticancer
Staphylococcus epidermidis ATTC 12228
25 μM
MIC
PMID10667861;8555423 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10667861/
RECORD: Rec_0095007 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. parapsilosis CP 1005
4.96 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
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