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MYP_118244
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Basic Information
Mastoparan B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C78H137N19O17
Standard
Sequence
LKLKSIVSWAKKVL
Physicochemical Analysis
1613.04 Da
10.48
3.76
3.55
0.2683
0.57
0.66
0.13
-31.77
160.00
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.95
-1.56
22.0
21.0
57.0
114.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0410708 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anticancer
Escherichia coli NIHJ JC-2
50 μM
MIC
PMID10667861;8555423 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10667861/
RECORD: Rec_0415700 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. parapsilosis CP 1007
4.96 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0418070 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Edema inducer
Guinea-pig erythrocytes
30 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8896194/ PMID8896194 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8896194/
RECORD: Rec_0427213 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. glabrata CG 1010
9.92 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
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