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MYP_118244
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Basic Information
Mastoparan B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C78H137N19O17
Standard
Sequence
LKLKSIVSWAKKVL
Physicochemical Analysis
1613.04 Da
10.48
3.76
3.55
0.2683
0.57
0.66
0.13
-31.77
160.00
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.95
-1.56
22.0
21.0
57.0
114.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006395 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiopolymers. 1995 Dec;36(6):793-801. | http://www.ncbi.nlm.nih.gov/pubmed/8555423 PMID8555423 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0028164 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
S. Choleraesuis, S. enterica serovar typhimurium CCRC12947, V. parahamelytics CCRC10806
32-64 μg/mL
MIC
PaperInteraction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity
RECORD: Rec_0044248 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Klebsiella pneumoniae CCRC10694
128 μg/mL
MIC
PaperInteraction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity
RECORD: Rec_0053066 VERIFIED: YES
Provenance & Taxonomy
Vespa basalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2091
2.52 μM
MIC
PMID8555423;35209228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8555423/
RECORD: Rec_0060851 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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