Peptide Database

Peptide NameSarcotoxin-1B (Sarcotoxin IB)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC306H499N89O81S

DescriptionStandard

        MNFNKVFIFVALILAVFAGQSQAGWLKKIGKKIERVGQHTRDATIQVIGVAQQAANVAATARG
    

Molecular Weight6752.85 Da

Isoelectric Point (pI)11.12

Net Charge (pH 7.0)5.59

Net Charge (pH 7.4) 5.31

Charge Density (pH 7.0) 0.0887

GRAVY Index0.31

Hydrophobic Moment 0.94

Boman Index0.16

Instability Index26.43

Aliphatic Index 105.40

Aromaticity 0.0794

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2771.12

LogP -25.99

H-bond Donors 95.0

H-bond Acceptors 89.0

Rotatable Bonds 230.0

Heavy Atoms 477.0

Ring Count 7.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171946 VERIFIED: YES

Provenance & Taxonomy

OrganismSarcophaga peregrina [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytotoxic Non-hemolytic

TargetGram-negative and Gram-positive bacteria