Peptide Database

Peptide NameBrevinin-2HS2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC127H224N36O42S2

DescriptionStandard

        GTVKDLLIGAGKSAAQSVLKALSCKLSNDC
    

Molecular Weight2991.48 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0580

GRAVY Index0.31

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index20.07

Aliphatic Index 110.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1273.23

LogP -16.16

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 105.0

Heavy Atoms 207.0

Ring Count 0.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198924 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)