Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 2

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC22H28N6O4

DescriptionStandard

VHW

Molecular Weight440.50 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.18

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0596

GRAVY Index0.03

Hydrophobic Moment 0.26

Boman Index0.50

Instability Index-2.93

Aliphatic Index 96.67

Aromaticity 0.3333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 165.99

LogP 0.71

H-bond Donors 6.0

H-bond Acceptors 5.0

Rotatable Bonds 10.0

Heavy Atoms 32.0

Ring Count 3.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006191 VERIFIED: YES

Provenance & Taxonomy

OrganismChlorella vulgaris [Bacterium]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity0.91±0.31 μM

MethodIC50

RECORD: Rec_0246549 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity0.91