Peptide Database

Peptide NameHsAp1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC143H239N43O41S

DescriptionStandard

        SGTSEKERESGRLLGVVKRLIVCFRSPFP
    

Molecular Weight3248.76 Da

Isoelectric Point (pI)10.04

Net Charge (pH 7.0)2.46

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0847

GRAVY Index-0.28

Hydrophobic Moment 0.70

Boman Index-0.14

Instability Index70.92

Aliphatic Index 83.79

Aromaticity 0.0690

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1373.23

LogP -14.30

H-bond Donors 51.0

H-bond Acceptors 45.0

Rotatable Bonds 109.0

Heavy Atoms 228.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209338 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative Hemolytic

TargetHuman red blood cells

Activity5; 35; 95; 100 %

MethodHemolysis

RECORD: Rec_0222439 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative

RECORD: Rec_0227971 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus megaterium AB 90008

Activity11.8 μM

MethodMIC

RECORD: Rec_0240775 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella oxytoca AB 2010143

Activity50.5 μM

MethodMIC

RECORD: Rec_0289008 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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