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MYP_118021
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Basic Information
HsAp1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C143H239N43O41S
Standard
Sequence
SGTSEKERESGRLLGVVKRLIVCFRSPFP
Physicochemical Analysis
3248.76 Da
10.04
2.46
2.23
0.0847
-0.28
0.70
-0.14
70.92
83.79
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1373.23
-14.30
51.0
45.0
109.0
228.0
4.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0085879 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
G- bacteria Escherichia coli DH5alpha; Escherichia coli JM109; E. cloacae subsp. cloacae AB 2010162; K. oxytoca AB 2010143
48-51 μM
MIC
PaperA novel class of antimicrobial peptides from the scorpion Heterometrus spinifer.
RECORD: Rec_0107417 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
P. putida; Pseudomonas fluorescens; Salmonella enterica AB 2010185
23-25 μM
MIC
PaperA novel class of antimicrobial peptides from the scorpion Heterometrus spinifer.
RECORD: Rec_0137535 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
HsAp
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPeptides. 2012 Dec;38(2):389-94 | http://www.ncbi.nlm.nih.gov/pubmed/23000095 PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0143074 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus AB 94004
23.6 μM
MIC
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0151014 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella enterica AB 2010185
25 μM
MIC
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
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