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MYP_117992
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Basic Information
Ocellatin-3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C98H168N28O29
Standard
Sequence
GVLDILKNAAKNILAHAAEQI
Physicochemical Analysis
2202.55 Da
6.75
-0.15
-0.41
-0.0072
0.44
0.67
0.22
49.88
149.05
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.91
-7.66
30.0
30.0
76.0
155.0
1.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004416 VERIFIED: YES
Provenance & Taxonomy
American frog [Animal]
Ocellatin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID15648972 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15648972/
RECORD: Rec_0010144 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus ocellatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli at uM. Hemolytic. provided by Erik Martin. Updated 7/2019
PaperOcellatins: new antimicrobial peptides from the skin secretion of the South American frog Leptodactylus ocellatus (Anura: Leptodactylidae)
RECORD: Rec_0122735 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Cytotoxic Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0130790 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus ocellatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 15648972 PMID15648972 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15648972/
RECORD: Rec_0187875 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus ocellatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 15648972 PMID15648972 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15648972/
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