Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC671H1120N172O183S11

DescriptionStandard

        MLIAWKSSCLILKNSVISIKRSLDKEIVLPISLGKSVSMKLFLVLIILQFEVPTDTARPRKCFSNITGYCRKKCEMGEIYEMACLNGKLCCVNEDKNKKHQKAPESPLPLPQPKGKIDYVILPTITLLTIQL
    

Molecular Weight14877.83 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.11

Charge Density (pH 7.0) 0.0646

GRAVY Index0.11

Hydrophobic Moment 0.54

Boman Index0.07

Instability Index48.28

Aliphatic Index 112.95

Aromaticity 0.0530

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5687.18

LogP -42.73

H-bond Donors 200.0

H-bond Acceptors 204.0

Rotatable Bonds 507.0

Heavy Atoms 1037.0

Ring Count 18.0

Amide Bonds 140.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386896 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal