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MYP_117975
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Basic Information
CRAMP-18
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C101H171N27O24
Standard
Sequence
GEKLKKIGQKIKNFFQKL
Physicochemical Analysis
2147.60 Da
10.30
4.76
4.54
0.2643
-0.89
0.76
-0.22
-31.39
86.67
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
880.71
-5.38
29.0
29.0
82.0
152.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0152739 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli KCTC 1682
50 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0331763 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
RECORD: Rec_0365627 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0379479 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Salmonella Typhimurium KCTC 1926
12.5 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0384749 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans
50 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
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