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MYP_117975
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Basic Information
CRAMP-18
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C101H171N27O24
Standard
Sequence
GEKLKKIGQKIKNFFQKL
Physicochemical Analysis
2147.60 Da
10.30
4.76
4.54
0.2643
-0.89
0.76
-0.22
-31.39
86.67
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
880.71
-5.38
29.0
29.0
82.0
152.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044867 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
S-aureus KCTC 1621
>50 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0068325 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Bacillus subtilis KCTC 1918
50 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0091970 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
A. fumigatus
100 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0100459 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
S. pyogenes KCTC 3096
50 μM
MIC
PaperCRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.
RECORD: Rec_0141221 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10973820/ PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
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