Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1198 amino acids

Chemical FormulaC5848H9127N1673O1802S35

DescriptionStandard

        MDNWSALFDGQTRYVLDINDSTVKADVLRFRGREALSEPFRWDIEFTSLHANIPPEQVLMKYASLRMRGGKNVHGMVTRLEWLSTSRDQSHYRLTLSSRLTLLGYTRQCAVFQNLSVPEVVEQVLRKHGLEGPDFEFRLERTYPARELITQWRETDLQFIQRILSEVGIYWRTEMDDVRGLDTCILADSQLNYQFDVQLPYSEPSGLFDGAADSVWDVRTWHNIATGTVATRDYNYRTATMPMDATVSVRSDAVTTGAHYRYTAPYRDAGDDTSPEPETESGAFYARIHHERELSRSARIHLFSNTGHLTPGQVLEPQGDVITALKEGVILTLVTFRGARDSRLHVSVWGVPYTERYCFRPAEIPRPLIPGTLPARIESREKNDIYPHLDEQGRYRVRLDFDRDATDPGYGYLWLRMAKPTAGESSGWHMPLTDGTEVAIAYSNGDIDLPYIACALHDSEHPDHVTRDNHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKSQLNSGHMVDSQGQRRGTGAELRTDEHGVIRAGKGLFVSADAQPKAQGEALDRDAALKEIDRLNQQLQQLEIAAEKAQALKADVDSQIQMFAQRLKPLNEALLMTAPEGMALTSGEDMQLAAGRNLAVNAGGDISVGTMGNLTALAGEKLGLFAHTGQLSLKSGEGAIDVQAQNASLRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGANAPAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSENNRYEFTPAHGADGPLITWTPERPEGSNLPSHTGSDIRPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTPKLHDEIHYRR
    

Molecular Weight132824.43 Da

Isoelectric Point (pI)5.63

Net Charge (pH 7.0)-27.47

Net Charge (pH 7.4) -29.80

Charge Density (pH 7.0) -0.0229

GRAVY Index-0.51

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index33.96

Aliphatic Index 75.12

Aromaticity 0.0793

Extinction Coeff. Reduced 171090.00

Extinction Coeff. Oxidized 171590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123819 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella diarizonae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID59204

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence

RECORD: Rec_0150729 VERIFIED: NO