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MYP_117960
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Basic Information
tetrapeptide
Hemostasis ▸ Antithrombotic activity
Standard
4 amino acids
C15H27N7O8
Standard
Sequence
RGDS
Physicochemical Analysis
433.42 Da
5.84
-0.24
-0.44
-0.0597
-2.30
0.52
-0.78
34.42
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
270.05
-4.79
10.0
8.0
14.0
30.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031975 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Estradiol
Bio-Activity Profile
-
Paper3D QSAR of novel estrogen-RGD peptide conjugates: Getting insight into structural dependence of anti-osteoporosis activity and side effect of estrogen in ERT Evidence URLhttps://doi.org/10.1016/j.bmc.2009.03.057
RECORD: Rec_0112487 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antithrombotic
PaperPierschbacher M. D., Ruoslahti E.. Cell attachment activity of fibronectin can be duplicated by small synthetic fragment of the molecule. Nature, 309, 30-33, 1984.
RECORD: Rec_0277045 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Estradiol-3-carboxymethyl ether
Bio-Activity Profile
-
PaperImproved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates Evidence URLhttps://doi.org/10.1021/jm070242a
RECORD: Rec_0341111 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Estradiol hemisuccinate
Bio-Activity Profile
-
PaperImproved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates Evidence URLhttps://doi.org/10.1021/jm070242a