Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2559H3979N655O741S14

DescriptionStandard

        MRTKQVPVLWAFVLLWNLYISSSQTVYPGIKARITQRALDYGVQVGTKVMEDMAKEIVIPDLKGSESLEFLKIDYVKYNFSNIKINAFSLPNTSLAFVPGVGIRALSNHGTANISANWEVRAPLFQDSGAADLFLSGIYFTGIVVLTRNNFGHPALELQDCHAQVSHARVSFSGGLSVLYNSFAEPMEKPILRNLNEMLCPIAIDQVEAFNANISALEVLTKIDNYTVLDCSLLSPPEVTENHLDLSLKGAFYPLESLVDPPFLPAPFELPESRDSMLYIGISEYFFKSASFAHFVTGALEITLSTKEISNYFNQNTQGIGSVLSKIAEIYILSQPFMLQIMATGPPVINLHPNNFSLEFPAAVAMLTQRENSTIEHIVSMDFIASTSVGLAILGQKLICSLSLNRFRLSLPENSHRDAKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFVNSDIQVLEDFLLISTDLTHETSSKQQPNLHSWGGLNLVNGPWREQPTH
    

Molecular Weight56224.82 Da

Isoelectric Point (pI)5.47

Net Charge (pH 7.0)-12.34

Net Charge (pH 7.4) -13.38

Charge Density (pH 7.0) -0.0243

GRAVY Index0.11

Hydrophobic Moment 0.73

Boman Index0.16

Instability Index34.67

Aliphatic Index 103.08

Aromaticity 0.0966

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48610.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222149 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria