Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC451H733N123O139S3

DescriptionStandard

        SRIHVTAIELPSASISLLPGSGIELVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVAAIFSTPLDNPGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight10198.58 Da

Isoelectric Point (pI)7.93

Net Charge (pH 7.0)0.63

Net Charge (pH 7.4) 0.30

Charge Density (pH 7.0) 0.0066

GRAVY Index0.17

Hydrophobic Moment 0.54

Boman Index0.16

Instability Index32.63

Aliphatic Index 101.56

Aromaticity 0.0521

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4166.33

LogP -47.75

H-bond Donors 148.0

H-bond Acceptors 145.0

Rotatable Bonds 333.0

Heavy Atoms 716.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0295481 VERIFIED: NO

Provenance & Taxonomy

OrganismChaetops frenatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria