Peptide Database

Peptide NameLantibiotic epilancin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC250H424N70O82S4

DescriptionStandard

        MNNSLFDLNLNKGVETQKSDLSPQSASVLKTSIKVSKKYCKGVTLTCGCNITGGK
    

Molecular Weight5850.72 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)4.47

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0812

GRAVY Index-0.32

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index32.36

Aliphatic Index 79.64

Aromaticity 0.0364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2510.61

LogP -33.41

H-bond Donors 89.0

H-bond Acceptors 91.0

Rotatable Bonds 205.0

Heavy Atoms 406.0

Ring Count 3.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0241928 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0310490 VERIFIED: NO