‹ ›
MYP_117866
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ HMG-CoA Reductase Inhibitory
Metabolic ▸ Lipid metabolism ▸ Cholesterol-lowering
Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity
Standard
4 amino acids
C25H36N4O6
Standard
Sequence
LPYP
Physicochemical Analysis
488.58 Da
5.52
-0.24
-0.45
-0.0602
-0.17
0.21
0.39
86.50
97.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
153.27
0.86
4.0
6.0
9.0
35.0
3.0
3.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0304301 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypolipidemic HMG-CoA Reductase Inhibitory
HMG-CoA reductase
484.0
IC50
PaperKwon D. Y., Oh S. W., Lee J. S., Yang H. J., Lee S. H., Lee J. H., Lee Y. B., Sohn H. S.. Amino acid substitution of hypocholesterolemic peptides originated from glycinin hydrolyzate. Food Sci. Biotechnol., 11, 55-61, 2002.
RECORD: Rec_0396317 VERIFIED: NO
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cholesterol Metabolism Modulator
SREBP2, HepG2
RECORD: Rec_0412278 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
5.0
IC50
PaperDellafiora L., Pugliese R., Bollati C., Gelain F., Galaverna G., Arnoldi A., Lammi C.. "Bottom-Up" strategy for the identification of novel soybean peptides with angiotensin-converting enzyme inhibitory activity. J. Agric. Food Chem., 68, 2082-2090, 2020.