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MYP_117825
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Basic Information
Cruzioseptin-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C112H185N31O29
Standard
Sequence
GFLDVIKHVGKAALGVVTHLINQ
Physicochemical Analysis
2429.86 Da
8.61
0.93
0.63
0.0406
0.74
0.68
0.34
-8.48
143.91
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
956.63
-6.72
32.0
32.0
81.0
172.0
3.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0127890 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli
26.35 μM
MIC
RECORD: Rec_0140595 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli (26.3 uM), Staphylococcus aureus (6.6 uM)
PaperPeptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer.
RECORD: Rec_0214120 VERIFIED: YES
Provenance & Taxonomy
the splendid leaf frog,Cruziohyla calcarifer,South America [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans (13.2 uM)
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
RECORD: Rec_0221988 VERIFIED: YES
Provenance & Taxonomy
the splendid leaf frog,Cruziohyla calcarifer,South America [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli (26.3 uM)
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
RECORD: Rec_0285526 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
13.18 μM
MIC
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
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