Peptide Database

Peptide NamegB122Δ10-15

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC53H73N17O12

DescriptionStandard

        GHRRYFTFG
    

Molecular Weight1140.25 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.2051

GRAVY Index-1.04

Hydrophobic Moment 0.48

Boman Index-0.21

Instability Index77.87

Aliphatic Index 0.00

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 489.06

LogP -4.15

H-bond Donors 19.0

H-bond Acceptors 15.0

Rotatable Bonds 34.0

Heavy Atoms 82.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131234 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHerpes simplex virus type 1(HSV-1):comprehensive antiviral activity

Activity100 μM

MethodEC50

RECORD: Rec_0138774 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0377966 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-HSV Entry inhibition

TargetHerpes simplex virus type 1 (HSV-1)

Activity100 μM

MethodEC50

Half-LifeMammalian: 30 h; Yeast: >20 h; E. coli: >10 h

PaperMultiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection. | Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR. | Antimicrob Agents Chemother. 2009 Mar;53(3):987-96. | DOI:10.1128/AAC.00793-08 | PMID:19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/