Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length250 amino acids

Chemical FormulaC1208H1887N313O353S11

DescriptionStandard

        MPVETVCSRLSQSCHCHSSLFLVFTVTARIDDNTGIDFSLVGPPRATAQSLDLDLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTASIAYHKAGALVFEVTDAMIPKDTVFRLETSLLSAFIPQVSSLALPAQSSCTHGLCSVPGGISFQPVVDAQAYAILPNSSLAPLFLLSLVSSNTACGIFPPSLPTPQVESLQSIMNVLTSRVVLPRLNGENLLEGMGVLEHPPLRLLHPSGPAH
    

Molecular Weight26795.50 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-5.75

Net Charge (pH 7.4) -6.54

Charge Density (pH 7.0) -0.0230

GRAVY Index0.30

Hydrophobic Moment 0.51

Boman Index0.20

Instability Index52.64

Aliphatic Index 98.28

Aromaticity 0.0800

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237348 VERIFIED: NO

Provenance & Taxonomy

OrganismCatharus ustulatus (Russet-backed thrush) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria