Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC243H374N60O80S5

DescriptionStandard

        MEKFEYSNLIQEVSDSELDEILGAGNGVIKTVSHECKMNTWQFLFTCCS
    

Molecular Weight5576.25 Da

Isoelectric Point (pI)4.38

Net Charge (pH 7.0)-5.43

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.1108

GRAVY Index-0.14

Hydrophobic Moment 0.51

Boman Index0.09

Instability Index30.47

Aliphatic Index 75.51

Aromaticity 0.1020

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2278.57

LogP -22.68

H-bond Donors 80.0

H-bond Acceptors 81.0

Rotatable Bonds 189.0

Heavy Atoms 388.0

Ring Count 7.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262895 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

FamilyLantibiotic

Tax ID1358

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria