Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide WCW

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC25H27N5O4S

DescriptionStandard

WCW

Molecular Weight493.58 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0833

GRAVY Index0.23

Hydrophobic Moment 0.00

Boman Index0.64

Instability Index85.60

Aliphatic Index 0.00

Aromaticity 0.6667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 153.10

LogP 1.75

H-bond Donors 7.0

H-bond Acceptors 5.0

Rotatable Bonds 10.0

Heavy Atoms 35.0

Ring Count 4.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089030 VERIFIED: YES

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity49.50±3.88 μM

MethodIC50

RECORD: Rec_0224497 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity49.5

MethodIC50