Peptide Database

Peptide NameMauriporin

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC246H405N71O65

DescriptionStandard

        FKIGGFIKKLWRSKLAKKLRAKGRELLKDYANRVINGGPEEEAAVPAE
    

Molecular Weight5397.28 Da

Isoelectric Point (pI)10.09

Net Charge (pH 7.0)5.77

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1202

GRAVY Index-0.59

Hydrophobic Moment 0.79

Boman Index-0.15

Instability Index44.55

Aliphatic Index 89.58

Aromaticity 0.0833

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2235.43

LogP -17.06

H-bond Donors 78.0

H-bond Acceptors 71.0

Rotatable Bonds 189.0

Heavy Atoms 382.0

Ring Count 7.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272374 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus mauritanicus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Cytotoxic

Targetcancer cell line

Activity4.4-7.8 μM

MethodIC50