MYP_117590
Basic Information
Dermaseptin-S1 (1-15)[W3HPA]
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antifungal
Antiviral
Antiviral Anti-Herpesvirus Anti-HSV
Antiviral Antiviral mechanism Viral entry inhibition
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
ALXKTMLKKLGTMAL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0389525 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'X' at position 3 indicates Nal (3-[1-naphthyl]alanine)
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
RECORD: Rec_0392896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'X' at position 3 indicates Nal (3-[1-naphthyl]alanine)
Bio-Activity Profile
Antimicrobial Antiviral
HSV-1:inhibition of virus infection in Vero cells
2.7 μM
IC50
RECORD: Rec_0413457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'X' at position 3 indicates Nal (3-[1-naphthyl]alanine)
Bio-Activity Profile
Antimicrobial Antiviral
RECORD: Rec_0415401 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
HSV-1
RECORD: Rec_0418158 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus subtilis ATCC 9466
11.2 μM
MIC
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