Peptide Database

Peptide NameBeta-defensin 125 (Beta-defensin 25, DEFB-25; Defensin, beta 125; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC244H396N80O68S6

DescriptionStandard

        SFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRR
    

Molecular Weight5730.64 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)5.58

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.1187

GRAVY Index-0.69

Hydrophobic Moment 0.60

Boman Index-0.31

Instability Index76.26

Aliphatic Index 72.55

Aromaticity 0.0851

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2461.04

LogP -25.84

H-bond Donors 96.0

H-bond Acceptors 82.0

Rotatable Bonds 193.0

Heavy Atoms 398.0

Ring Count 8.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008797 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0031051 VERIFIED: NO