Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC96H150N26O33S4

DescriptionStandard

        GIVDQCCTGVCSLYQLQNYCN
    

Molecular Weight2324.63 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.55

Charge Density (pH 7.0) -0.0610

GRAVY Index0.22

Hydrophobic Moment 0.39

Boman Index0.15

Instability Index17.70

Aliphatic Index 83.33

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.99

LogP -12.18

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 74.0

Heavy Atoms 159.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174949 VERIFIED: YES

Provenance & Taxonomy

OrganismHystrix cristata [Animal]

FamilyInsulin

Tax ID10137

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0308857 VERIFIED: YES

Provenance & Taxonomy

OrganismHystrix cristata [Animal]

FamilyInsulin

Tax ID10137

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour