Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC413H650N114O125S13

DescriptionStandard

        MKTFSVAVAVAVVLTFICVQQSSAVPVTEQEQEQEEPMSMDYPAAAHEEASVDSWKMLYNSRHKRGIKCRFCCGCCTPGICGVCCRF
    

Molecular Weight9629.11 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0161

GRAVY Index0.07

Hydrophobic Moment 0.45

Boman Index0.06

Instability Index71.80

Aliphatic Index 64.94

Aromaticity 0.0805

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3812.82

LogP -40.26

H-bond Donors 140.0

H-bond Acceptors 139.0

Rotatable Bonds 313.0

Heavy Atoms 665.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086094 VERIFIED: NO

Provenance & Taxonomy

OrganismSarotherodon galilaeus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal