Peptide Database

Peptide NameFMRFamide-like peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC52H76N16O13

DescriptionStandard

        NVGSHGFLRF
    

Molecular Weight1133.26 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0847

GRAVY Index0.08

Hydrophobic Moment 0.44

Boman Index0.16

Instability Index9.40

Aliphatic Index 68.00

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 479.12

LogP -4.69

H-bond Donors 17.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 81.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120555 VERIFIED: YES

Provenance & Taxonomy

OrganismCallinectes sapidus [Animal]

FamilyFMRFamide related peptide

Tax ID6763

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0140443 VERIFIED: NO

Provenance & Taxonomy

OrganismCallinectes sapidus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0168956 VERIFIED: YES

Provenance & Taxonomy

OrganismCallinectes sapidus [Animal]

FamilyFMRFamide-like peptide

Tax ID6763

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0255976 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/