‹ ›
MYP_117480
← PREVIOUS NEXT → BACK
Basic Information
FK13-a7 (Derived from FK13)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C97H146N34O14
Standard
Sequence
WKRWVRRWKRWLR
Physicochemical Analysis
2012.42 Da
12.00
6.76
6.55
0.5199
-1.99
1.15
-0.79
253.41
52.31
0.3077
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
837.22
-1.61
35.0
21.0
64.0
145.0
8.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0027774 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacteria: Escherichia coli(KCTC 1682)
4 μM
MIC
PaperLL-37-derived membrane-active FK-13 analogs possessing cell selectivity, anti-biofilm activity and synergy with chloramphenicol and anti-inflammatory activity PMID28161291 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28161291/
RECORD: Rec_0030544 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCTC 1621
2 μM
MIC
PMID28161291 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28161291/
RECORD: Rec_0030793 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa CCARM 2109
4 μM
MIC
PMID28161291 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28161291/
RECORD: Rec_0043502 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium ATCC 51559
4 μM
MIC
PMID28161291 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28161291/
RECORD: Rec_0046262 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
138 μM
Hemolysis
PMID28161291 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28161291/
1 2 3 ... 6 NEXT LAST
Showing 5 records on this page · Page 1 of 6