Peptide Database

Peptide NameSLAY-screened peptide P5216

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC83H124N20O18

DescriptionStandard

        SVSAKWRPVLLFWT
    

Molecular Weight1690.00 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.1042

GRAVY Index0.46

Hydrophobic Moment 0.25

Boman Index0.24

Instability Index26.06

Aliphatic Index 104.29

Aromaticity 0.2143

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 613.02

LogP -1.92

H-bond Donors 23.0

H-bond Acceptors 20.0

Rotatable Bonds 49.0

Heavy Atoms 121.0

Ring Count 6.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411034 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/