Peptide Database

Peptide NameHuwentoxin-IIIa

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC164H255N47O45S7

DescriptionStandard

        DCAGYMRECKEKLCCSGYVCSSRRKWCVLPAPW
    

Molecular Weight3829.52 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0819

GRAVY Index-0.30

Hydrophobic Moment 0.37

Boman Index-0.11

Instability Index69.71

Aliphatic Index 47.27

Aromaticity 0.1212

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1485.33

LogP -13.33

H-bond Donors 60.0

H-bond Acceptors 55.0

Rotatable Bonds 121.0

Heavy Atoms 263.0

Ring Count 8.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097998 VERIFIED: YES

Provenance & Taxonomy

OrganismSelenocosmia huwena [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-14; 9-20; 15-27

Bio-Activity Profile

Function

Toxin

Targetcockroach

Activity192000000 μM

MethodED50