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MYP_117256
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Basic Information
Tigerinin-2 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
12 amino acids
C63H101N17O13S2
Standard
Sequence
RVCFAIPLPICH
Physicochemical Analysis
1368.71 Da
8.08
0.83
0.55
0.0690
1.31
0.31
0.38
49.98
130.00
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
456.42
-1.11
17.0
17.0
38.0
95.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052103 VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus tigerinus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID11031261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11031261/
RECORD: Rec_0052374 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
3-11
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal
yeast Saccharomyces cerevisiae ATCC 8530
100 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
RECORD: Rec_0052522 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
3-11
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal
Micrococcus luteus MT 166
20 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
RECORD: Rec_0068266 VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus tigerinus [Animal]
Tigerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
3-11
Bio-Activity Profile
Antimicrobial Antifungal
PaperK.P. Sai et al. / The Journal of Biological Chemistry 276 (2001) 2701-2707. Tigerinins: Novel Antimicrobial Peptides from the Indian Frog Rana tigerina Evidence URLhttps://www.uniprot.org/uniprotkb/P82652/entry
RECORD: Rec_0078409 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
3-11
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal
P. putida NCIM 2102
50 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
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