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MYP_117153
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Basic Information
M-lycotoxin-Ls3b (M-LCTX-Ls3b) (Lycocitin-2)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C89H153N25O24S
Standard
Sequence
GRLQAFLAKMKEIAAQTL
Physicochemical Analysis
1989.38 Da
9.99
1.76
1.55
0.0978
0.22
0.41
0.07
56.37
108.89
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
815.67
-6.17
28.0
27.0
70.0
139.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0360614 VERIFIED: NO
Provenance & Taxonomy
Wolf spider [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0365789 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37265
RECORD: Rec_0372708 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
5.02-10.05 μM
MIC
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
RECORD: Rec_0376242 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
RECORD: Rec_0388983 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus 209P
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
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