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MYP_117153
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Basic Information
M-lycotoxin-Ls3b (M-LCTX-Ls3b) (Lycocitin-2)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C89H153N25O24S
Standard
Sequence
GRLQAFLAKMKEIAAQTL
Physicochemical Analysis
1989.38 Da
9.99
1.76
1.55
0.0978
0.22
0.41
0.07
56.37
108.89
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
815.67
-6.17
28.0
27.0
70.0
139.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177086 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
3.14-6.29 μM
MIC
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
RECORD: Rec_0185197 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Lycocitin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Mass Spectrom. 2004 Feb;39(2):193-201. | http://www.ncbi.nlm.nih.gov/pubmed/14991689 PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
RECORD: Rec_0188630 VERIFIED: NO
Provenance & Taxonomy
Lycosa singoriensis,Aranea singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus, Bacillus subtilis, Escherichia coli, P. aeruginosa, C. albicans
RECORD: Rec_0219247 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
RECORD: Rec_0252689 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6533
PMID14991689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991689/
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