Peptide Database

Peptide NameCyclotide psyle D

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC138H223N37O43S6

DescriptionStandard

        GIPCGESCVFIPCTVTALLGCSCQNKVCYRD
    

Molecular Weight3280.86 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0095

GRAVY Index0.57

Hydrophobic Moment 0.30

Boman Index0.19

Instability Index27.39

Aliphatic Index 81.61

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1268.59

LogP -14.59

H-bond Donors 49.0

H-bond Acceptors 49.0

Rotatable Bonds 102.0

Heavy Atoms 224.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0174720 VERIFIED: NO

Provenance & Taxonomy

OrganismPsychotria leptothyrsa [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic

RECORD: Rec_0314290 VERIFIED: YES