Peptide Database

Peptide NameInsectotoxin I4

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC153H246N50O46S11

DescriptionStandard

        MCMPCFTTDHNMAKKCRDCCGGNGKCFGPQCLCNR
    

Molecular Weight3874.61 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)2.51

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0716

GRAVY Index-0.41

Hydrophobic Moment 0.48

Boman Index-0.13

Instability Index42.95

Aliphatic Index 14.00

Aromaticity 0.0571

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1553.10

LogP -20.85

H-bond Donors 60.0

H-bond Acceptors 61.0

Rotatable Bonds 127.0

Heavy Atoms 260.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022923 VERIFIED: NO

Provenance & Taxonomy

OrganismButhus eupeus,Mesobuthus eupeus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-19; 5-26; 16-31; 20-33

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0065939 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic