Peptide Database

Peptide NameKininogen-1

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC387H619N117O106S4

DescriptionStandard

        VERNVPESEEKTEQFLRDLFEISRLQRRPAGFTPFRGKFHSQSLRGLSETKRIYNAIWPCKHCNKCKPGLLCKK
    

Molecular Weight8735.04 Da

Isoelectric Point (pI)9.80

Net Charge (pH 7.0)7.88

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.1065

GRAVY Index-0.87

Hydrophobic Moment 0.79

Boman Index-0.26

Instability Index73.91

Aliphatic Index 63.24

Aromaticity 0.0946

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3659.19

LogP -35.61

H-bond Donors 132.0

H-bond Acceptors 120.0

Rotatable Bonds 296.0

Heavy Atoms 614.0

Ring Count 15.0

Amide Bonds 79.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0038048 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyKininogen

Tax ID8348

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Myotropic Receptor modulation

Targetvitro relaxation of rat arterial smooth muscle

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0090030 VERIFIED: YES